A specimen drawn from an indwelling catheter that was contaminated by heparin would be indicated by:

References:

http://www.cdc.gov/ncidod/hip

http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5110a1.htm

http://www.cdc.gov/niosh/topics/bbp/sharps.html

Gillies D, O’Riordan L, Wallen M, et al. Optimal timing for intravenous administration set replacement. Cochrane Database Syst Rev 2005;(4):CD003588.

http://www.cdc.gov/mmwr/preview/mmw.htm/rr5110a1.htm

Luebke, M., et al. (1998). Am J Infection Control, 26: pp. 437-441.

Plott, R., Wagner, R., Tyring, S. (1990). Archive Dermatology, 126: pp 1441-1444.

Salzman, M., Isenberg, H., Rubin, L. (1993). Journal of Clinical. Microbiology, 31: pp. 475-479

Developed by: Brenda Morgan, CNS, CCTC 1988

Revised: June 30, 2016, Reviewed: February 5, 2021, Reviewed January 19, 2022

. 1988 Nov;17(6 Pt 1):662-6.

Affiliations

• PMID: 3192412

Evaluation of coagulation studies from heparinized arterial lines with use of Lab-Site high-pressure tubing

R S Cicala et al. Heart Lung. 1988 Nov.

Abstract

Heparinized arterial catheters are commonly used in critically ill patients to monitor pressures and to collect blood for laboratory analysis. To remove the heparinized fluid used to keep these lines patent large volumes of blood are often withdrawn and discarded or calculations of tube volume must be made. Repeated violation of stopcocks may lead to contamination and infection of arterial lines. In addition, discarded blood has become an increasing concern as a source of infection for health care personnel. This study evaluates the efficacy of noncompliant arterial line tubing that contains two polymer sampling ports permanently placed at prefixed distances such that if blood is withdrawn to the distal port, undiluted arterial blood can then be withdrawn from the proximal port. Blood from arterial lines that consisted of 20-gauge catheters connected to Lab-Site tubing was withdrawn in the method suggested by the manufacturer with no removal or wasting of excess blood from the system. Prothrombin time (PT) and activated partial thromboplastin time (aPTT) studies performed on this sample were compared with those performed on a simultaneously drawn venous sample. Regression analysis showed a correlation coefficient of 0.966 for PT and 0.935 for aPTT, demonstrating an excellent correlation for the technique. The average arterial PT was 0.12 seconds less than venous control and the average arterial aPTT was 0.49 seconds greater than control. Neither of these differences was significant. We conclude that this type of high-pressure tubing allows accurate blood samples to be obtained from arterial lines without the necessity of precise calculations or blood wastage.

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