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Advantages: Routes are easy and comfortable to administer, convenient, economical; may produce local or systemic effects; and rarely cause anxiety for patient.

Disadvantages: Routes are avoided when patient has alterations in GI function (e.g., nausea and vomiting), with reduced GI motility (after general anesthesia or bowel inflammation), and with surgical resection of portion of GI tract.

Gastric secretions destroy some medications. Oral administration is contraindicated in patients who are NPO and unable to swallow (e.g., patients with neuromuscular disorders, esophageal strictures, and mouth lesions).

Do not give oral medications when patient has gastric suction or before certain diagnostic tests or surgery.

An unconscious or confused patient is unable or unwilling to swallow or hold sublingual medication under tongue or buccal medication in cheek.

Oral medications sometimes irritate lining of GI tract, discolor teeth, or have an unpleasant taste.

Which route is used to administer a suppository?

Rectal route Many drugs that are administered orally can also be administered rectally as a suppository. In this form, a drug is mixed with a waxy substance that dissolves or liquefies after it is inserted into the rectum. Because the rectum's wall is thin and its blood supply rich, the drug is readily absorbed.

Which route is generally preferred for the administration?

Oral administration of medication is a convenient, cost-effective, and most commonly used medication administration route.

What is the probable route of administration advised for a patient prescribed a suppository form of medication?

Suppository should be against rectal mucosa for absorption and therapeutic action.

Which is the most convenient route of administration and the one most commonly used?

The oral route is generally the most convenient and costs the least. However, some drugs can cause gastrointestinal tract irritation. For drugs that come in delayed release or time-release formulations, breaking the tablets or capsules can lead to more rapid delivery of the drug than intended.

What are the route of administration of drugs?

Drug Administration.
Taken by mouth (orally).
Given by injection into a vein (intravenously, IV), into a muscle (intramuscularly, IM), into the space around the spinal cord (intrathecally), or beneath the skin (subcutaneously, sc).
Placed under the tongue (sublingually) or between the gums and cheek (buccally).