What factors are most important in influencing the movement of fluid between compartments quizlet?

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Terms in this set (83)

21.1 Introduction

Goal:
1. Explain the balance concept.
2. Explain the importance of water and electrolyte balance.

what does Balance mean for water and electrolytes

- state of constancy
-For water and electrolytes that means equal amounts enter and leave the body

What two (2) mechanisms maintain this balance?

Mechanisms that
1.replace lost water and electrolytes and
2. excrete excesses

What does balance result in?

it results in stability of the body at all times

are water and electrolyte balance interdependent or one in the same?

interdependent

21.2: Distribution of Body Fluids

Goal:
1. Describe how body fluids are distributed in compartments.
2. Explain how fluid composition varies among compartments and how fluids move from one compartment to another.

How are body fluids distributed

not uniformly, instead they occupy compartments of different volumes that contain varying compositions

Water and electrolyte movement between these compartments is regulated for what reason?

to stabilize their distribution and the composition of body fluids

This next section is on Fluid Compartments

...

How much of water weight do families and males hold

An average adult
-female is about 52% water by weight, and a
- male about 63% water by weight

Hoe many liters of water is their in the body

40 (this includes dissolved electrolytes)

What two major components is this water distributed into?

1.Intracellular fluid
2.Extracellular fluid

Intracellular fluid

63% - fluid inside cells

Extracellular fluid

37% - fluid outside cells
Extracellular fluids are generally similar in composition including high concentrations of sodium, calcium, chloride and bicarbonate ions

Interstitial fluid

Fluid between cells
Intracellular fluids have high concentrations of potassium, magnesium, phosphate, and sulfate ions

Blood plasma

A fluid portion of the blood that contains 90 percent water and 10 percent other
Blood plasma has more proteins than interstitial fluid or lymph

Lymph

A type of white blood cell that make antibodies to fight off infections

Transcellular fluid

separated from other extracellular fluids by epithelial layers

Cerebrospinal fluid

Fluid in the space between the meninges that acts as a shock absorber that protects the central nervous system.

Aqueous and vitreous humors

liquid that keeps the eye in shape

Synovial fluid

Lubricant that makes smooth joint movements possible.

Serous fluid

lubricates the organs and allows them glide without friction

What are the two major factors that regulate the movement of water and electrolytes from one fluid compartment to another

1. Hydrostatic pressure
2. Osmotic pressure

Describe the Movement of Fluid Between Compartments 4 steps

1. Fluid leaves plasma
at arteriolar end of
capillaries because
outward force of
hydrostatic pressure
2. Fluid returns to
plasma at venular
ends of capillaries
because inward force
of colloid osmotic
pressure predominates
3. Hydrostatic pressure
within interstitial
spaces forces fluid
into lymph capillaries
4. Interstitial fluid is
in equilibrium with
transcellular and
intracellular fluids

21.3 Water balance

Goal:
1. List the routes by which water enters and leaves the body.
2. Explain the regulation of water input and water output.

When does Water balance exists?

when water intake equals water output

what does Homeostasis require

it requires control of both water intake and water output

How does water intake vary? (Three ways)

The volume of water gained each day varies among individuals averaging about 2,500 milliliters daily for an adult:
1. 60% from drinking
2. 30% from moist foods
3. 10% as a bi-product of oxidative metabolism of nutrients called water of metabolism

Describe an average daily intake of water

-Total intake (2,500 mL)
-Water in beverages (1,500 mL or 60%)
-Water in moist food (750 mL or 30%)
-Water of metabolism (250 mL or 10%)

Describe an average daily output of water

-Total output (2,500 mL)
-Water lost in urine (1,500 mL or 60%)
-Water lost through skin and lungs (700 mL or 28%)
-Water lost in feces (150 mL or 6%)
-Water lost in sweat (150 mL or 6%)

Describe the regulation of water intake (6 steps)

1. the body loses as lithe as 1% of its water
2. An increase in the osmotic pressure of extracellular fluid due to water loss stimulates osmoreceptors in the thirst center
3. Activity in the hypothalamus causes the person to feel thirsty an to seek water
4. Drinking and the resulting distention of the stomach by water stimulates nerve implies that inhibit the thirst center
5. Water is absorbed through the walls of the stomach and the small intestines
6. the osmotic pressure of the extracellular fluid returns to normal

water normally enter the body through the what?

mouth

water can be lost by 5 main ways name them

1. Urine (60% loss)
2. Feces (6% loss)
3. Sweat (sensible perspiration) (6% loss)
4. Evaporation from the skin (insensible perspiration)
5. The lungs during breathing
(Evaporation from the skin and the lungs is a 28% loss)

describe the events in the regulation of water output during dehydration (6 steps)

1. extracellular fluid becomes osmotically more concentrated
2. osmoreceptors in the hypothalamus are stimulated by the increase in osmotic pressure of body fluids
3. the hypothalamus signals the posterior pituitary gland to release ADH into the blood
4. blood caries ADH to the kidneys
5. ADH causes the distal convoluted tubules and collecting ducts to increase water reabsorption
6. Urine output decreases, and further water loss is minimized

describe the events in the regulation of water output during excess water intake (5 Steps)

1. extracellular fluid becomes osmotically concentrated
2. this change stimulates osmoreceptors in the hypothalamus
3. the posterior pituitary gland decrees ADH release
4. Renal tubules decrease water reabsorption
5. Urine output increases and excess water is excreted

what does the The osmoreceptor-ADH mechanism in the hypothalamus do?

it regulates the concentration of urine produced in the kidney

21.4: Electrolyte Balance

Goal:
1. List the routes by which electrolytes enter and leave the body.
2. Explain the regulation of the input and the output of electrolytes.

When does An electrolyte balance exists?

when the quantities of electrolytes the body gains equals those lost

name electrolytes that have the greatest importance

The electrolytes of greatest importance to cellular functions are the ones that release sodium, potassium, calcium, magnesium, chloride, sulfate, phosphate, bicarbonate, and hydrogen ions

where do these electrolytes primarily obtained from?

These ions are primarily obtained from foods, but some are from water and other beverages, and some are by-products of metabolism

how does a person obtain sufficient electrolytes?

by responding to hunger and thirst

what kind of craving could an electrolyte deficiency cause?

a salt craving

how does the body lose(output) electrolytes? (3)

-The body loses some electrolytes by perspiring (more on warmer days and during strenuous exercise)
- Some are lost in the feces
- The greatest output is as a result of kidney function and urine output

What help regulate electrolyte output

The concentrations of positively charged ions, such as
1.sodium (Na+),
2.potassium (K+) and
3.calcium (Ca+2)

what are these three ions important for?

These ions are vital for nerve impulse conduction, muscle fiber contraction, and maintenance of cell membrane permeability

What is particular about sodium ions?

Sodium ions account for nearly 90% of the positively charged ions in extracellular fluids

please study slide 20

...

21.5: Acid-Base Balance

Goal:
1. Explain acid-base balance.
2. Identify how pH number describes the acidity and alkalinity of a body fluid.
3. List the major sources of hydrogen ions in the body.
4. Distinguish between strong acids and weak acids.
5. Explain how chemical buffer systems, the respiratory center, and the kidneys keep the pH of body fluids relatively constant.

What are acids

electrolytes that ionize in water and release hydrogen ions

what are bases

substances that combine with hydrogen ions

What does Acid-base balance entail an why is this important?

it entails regulation of the hydrogen ion concentrations of body fluids
-This is important because slight changes in hydrogen ion concentrations can alter the rates of enzyme-controlled metabolic reactions, shift the distribution of other ions, or modify hormone actions

pH number

indicates the degree to which a solution is acidic or basic (alkaline).

more acid the solution, the __________ its pH

lower

The more alkaline the solution, _________ its pH

higher

study slide 23

...

Strong acids ionize _______ completely and release ______ H+.
Give an example

more...more
Ex: HCl

Weak acids ionize _______ completely and release _____ H+
Give an example

less...fewer
Ex: H2CO3

Strong bases ionize _____ completely and release _____ OH- or other negative ions

more...more

Weak bases ionize ______ completely and release _______ OH- or other negative ions

less...fewer

what two things could threaten the internal environment in the body fluids

Either an
1. acid shift or an
2. alkaline (basic) shift
in the body fluids could threaten the internal environment

what produces more acid than base, give an example

normal metabolic reactions
example:cellular metabolism of glucose, fatty acids, and amino acids

Maintenance of acid-base balance usually eliminates acids in one of three ways: name the three ways.

1. Acid-base buffer systems
2. Respiratory excretion of carbon dioxide
3. Renal excretion of hydrogen ions

Chemical buffer systems

-They are in all body fluids and are based on chemicals that combine with excess acids or bases.
-Various regulators of hydrogen ion concentration operate at different rates
-function rapidly
-First line of defense against pH shift

Respiratory and renal (physiological buffers)

-mechanisms function more slowly
-Second line of defense against pH shift

Name the three (3) buffering systems that correspond with Chemical
buffer system

1. Bicarbonate buffer system
2. Phosphate buffer system
3. Protein buffer system

Name the two (2) mechanisms the correspond with the Physiological
buffers

1. Respiratory mechanism (CO2 excretion)
2. Renal mechanism (H+ excretion)

Bicarbonate buffer system

-The bicarbonate ion (HC03-) converts a strong acid to a weak acid
- Carbonic acid (H2C03) converts a strong base to a weak base
H+ + HCO3- -> H2CO3 -> H+ + HCO3-

Phosphate buffer system

-The monohydrogen phosphate ion (HPO4-2)converts a strong acid to a weak acid
-The dihydrogen phosphate ion (H2PO4-)converts a strong base to a weak base
H+ + HPO4-2 -> H2PO4- -> H+ + HPO4-2

Protein buffer system

-NH3+ group of an amino acid or protein, releases a hydrogen ion in the presence of excess base
-COO- group of an amino acid or protein, accepts a hydrogen ion in the presence of excess acid

The respiratory center in the brainstem helps regulate what?

it helps regulate hydrogen ion concentrations in the body fluids by controlling the rate and depth of breathing

explain what happens if body cells increase their production of CO2...
6 steps

1.Cells increase production of CO2
2.CO2 reacts with H2O to produce H2CO3
3.H2CO3 releases H+
4.Respiratory center is stimulated
5.Rate and depth of breathing increase
6.More CO2 is eliminated through lungs

Nephrons help regulate what?

theyhelp regulate the hydrogen ion concentration of body fluids by excreting hydrogen ions in the urine

21.6: Acid-Base Imbalances

Goal:
1. Describe the causes and consequences of increase or decrease in body fluid pH.

Chemical and physiological buffer systems ordinarily maintain the hydrogen ion concentration of body fluids within what kind of pH ranges?

Narrow

what may disturb the acid-base balance?

Abnormal conditions

what does Acidosis result from?

results from the accumulation of acids or loss of bases, both of which cause abnormal increases in the hydrogen ion concentrations of body fluids

what does Alkalosis result from?

results from a loss of acids or an accumulation of bases accompanied by a decrease in hydrogen ion concentrations

what are the Two major types of acidosis

1. respiratory acidosis and
2. metabolic acidosis

study figures on slide 33

...

Respiratory alkalosis develops as a result of what?

as a result of hyperventilation

Metabolic alkalosis develops as a result of what?

results from a great loss of hydrogen ions or from a gain in bases, both accompanied by a rise in the pH of blood

process of Respiratory alkalosis (6 steps)

1. anxiety, fever, poisoning, high attitude
2. hyperventilation
3. excessive loss of CO2
4. decrease in concentration of H2Co3
5. Decrease in Concentration of H2
6. Respiratory alkalosis

process of Metabolic alkalosis (4 steps)

1. gastris damage or vomiting with los of gastric secretions
2. loss of acids
3. net increase in alkaline substances
4. Metabolic alkalosis

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What factors are most important in influencing the movement of fluid between compartments?

Fluid Movement between Compartments. Hydrostatic pressure, the force exerted by a fluid against a wall, causes movement of fluid between compartments. The hydrostatic pressure of blood is the pressure exerted by blood against the walls of the blood vessels by the pumping action of the heart.

What factors are most important and influencing the movement of fluid between compartments quizlet?

the major influence controlling the movement of water between intracellular and extracellular spaces is osmotic pressure. sodium concentration is the primary determinant of water location.

Which two factors make major contributions to the movement of fluid from one compartment to another quizlet?

Two major factors contribute to the movement of fluid from one compartments to another: hydrostatic pressure and osmotic pressure. Blood vessels, fluid leaves the plasma at arteriolar ends of capillaries and enters interstitial spaces because of the net outward force of hydrostatic pressure (blood pressure).

Which two factors make major contributions to the movement of fluid from one compartment to another?

Fluid is moved by a combination of osmotic and hydrostatic pressures. The osmotic pressure results from differences in solute concentrations across cell membranes. Hydrostatic pressure results from the pressure of blood as it enters a capillary system, forcing some fluid out of the vessel into the surrounding tissues.